Do not blame the SSRIs: blame the Hamilton Depression Rating Scale
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Do not blame the SSRIs: blame the Hamilton Depression Rating Scale.
Dear Editor, In their recent paper entitled ‘Selective serotonin reuptake inhibitors versus placebo in patients with major depressive disorder. A systematic review with meta-analysis and Trial Sequential Analysis’ (1), Jakobsen et al. conclude that ‘The observed harmful effects seem to outweigh the potential small beneficial clinical effects of SSRIs, if they exist’ (1). In a follow-up article ...
متن کاملThe Hamilton Rating Scale for Depression.
The Hamilton Rating Scale for Depression (often abbreviated to HRSD, HDRS or Ham-D) was written in the late 1950s by Max Hamilton, a psychiatrist at Leeds University and originally designed to evaluate the performance of the first group of antidepressants [1]. The scale is still widely used to measure the effectiveness of antidepressant medication in clinical trials. For more than 40 years, it ...
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In all clinical and research work, it is important not only to have uniform diagnostic criteria but also some means of objectively quantifying the presence and severity of the illness being studied. For this purpose, a number of ra t ing scales have been devised for depressive disorders, probably the single most commonly used one being the Hamilton Ra t ing Scale (Hamil ton, 1960). The total sc...
متن کاملUse of the Hamilton Rating Scale for Depression and the Carroll Self-Rating Scale in adolescents.
The relationship of clinicians' ratings of depression in adolescents to self-rating is important to clinical research. The Hamilton Rating Scale for Depression (HRSD) and the Carroll Self-Rating Scale (CSRS) were compared in a study of 81 psychiatrically hospitalized adolescents. The correlation of CSRS and HRSD total scores in adolescents with melancholic major depression was 0.46, lower than ...
متن کاملRating depression over brief time intervals with the Hamilton Depression Rating Scale: standard vs. abbreviated scales.
Although antidepressant trials typically use weekly ratings to examine changes in symptoms over six to 12 weeks, antidepressant treatments may improve symptoms more quickly. Thus, rating scales must be adapted to capture changes over shorter intervals. We examined the use of the 17-item Hamilton Depression Rating Scale (HDRS) to evaluate more rapid changes. Data were examined from 58 patients w...
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ژورنال
عنوان ژورنال: Acta Neuropsychiatrica
سال: 2017
ISSN: 0924-2708,1601-5215
DOI: 10.1017/neu.2017.6